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Vaccin mot Alzheimers
Alzheimers är nog en av de sjukdomar där man kan tänka sig att chansa lite i behandling. Och nu har man hittat ett vaccin som i alla fall verkar fungera på möss.
Come on, give it a shot!
Läs mer: Vaccine thwarts the tangles of Alzheimer's | Science Blog
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Come on, give it a shot!
The antibodies raised by the vaccine must reach the brain by traversing the organ’s protective blockade, the blood brain barrier. “Normally antibodies aren’t getting into the brain in any large quantities,” said Dr. Sigurdsson. “In this animal model—and also in Alzheimer’s disease—there’s a breakdown of the blood brain barrier. In addition, it is well established that neurons have receptors that can bind to and promote uptake of antibodies and our studies seem to indicate that sick neurons that are accumulating tau aggregates take up more antibodies than healthy neurons. The antibodies then end up at the site where they can interact with pathological tau protein in the neuron, and promote its clearance.”
Läs mer: Vaccine thwarts the tangles of Alzheimer's | Science Blog
Levande virusvaccin effektivare på barn, avdödat på vuxna
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