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Discovering this basic neural circuitry turned out to be a key breakthrough in understanding anxiety. It showed that the anxiety response isn't necessarily caused by an external threat; rather, it may be traced to a breakdown in the mechanism that signals the brain to stop responding. Just as a car can go out of control due to either a stuck accelerator or failed brakes, it's not always clear which part of the brain is at fault. It may turn out that some anxiety disorders are caused by an overactive amygdala (the accelerator) while others are caused by an underactive prefrontal cortex (call it the brake).
Läs mer: TIME.com: The Science Of Anxiety -- Jun. 10, 2002 -- Page 3