Länk - Intressant om livslängd och neuroner

published Sep 21, 2007 05:37   by admin ( last modified Sep 21, 2007 05:37 )
So researchers restricted the diets of the flies and ran the same experiments. The calorie-restricted flies didn’t live any longer when p53 was reduced in the insulin-producing cells. This evidence supports the notion that p53 reduction is one of the direct effects of caloric restriction. Even more intriguing, Helfand said, is the fact that the 14 insulin-producing cells that seem to be critical for lifespan extension are the equivalent of beta cells in the human pancreas. Beta cells make and release insulin, the hormone that controls the level of glucose in the blood. The research team found that when p53 activity drops, so does insulin-responsive activity in the fat body, the major metabolic organ in the fruit fly.


Läs mer: Key to longer life (in flies) lies in just 14 brain cells | Science Blog